Epidemiological and clinical complexity of amoxicillin-clavulanate-resistant Escherichia coli.
نویسندگان
چکیده
Two hundred twelve patients with colonization/infection due to amoxicillin-clavulanate (AMC)-resistant Escherichia coli were studied. OXA-1- and inhibitor-resistant TEM (IRT)-producing strains were associated with urinary tract infections, while OXA-1 producers and chromosomal AmpC hyperproducers were associated with bacteremic infections. AMC resistance in E. coli is a complex phenomenon with heterogeneous clinical implications.
منابع مشابه
Increased multi-drug resistant Escherichia coli from hospitals in Khartoum state, Sudan.
BACKGROUND Multidrug-resistant Escherichia coli (MDR E. coli) has become a major public health concern in Sudan and many countries, causing failure in treatment with consequent huge health burden. OBJECTIVES To determine the prevalence and susceptibility of MDR E. coli isolated from patients in hospitals at Khartoum State. METHODS Between May to August 2011, E. coli (n = 232) isolated from ...
متن کاملVariety of beta-lactamases produced by amoxicillin-clavulanate-resistant Escherichia coli isolated in the northeastern United States.
This study analyzed the enzymatic basis and molecular epidemiology of amoxicillin-clavulanate-resistant Escherichia coli isolated by the microbiology laboratory of a United States tertiary care hospital. From October 1998 to December 1999, all E. coli isolates were screened for ampicillin-sulbactam resistance. Of 283 isolates that tested resistant to ampicillin-sulbactam, 69 unique patient isol...
متن کاملMultidrug-resistant enteroaggregative Escherichia coli associated with persistent diarrhea in Kenyan children.
To study the association of multidrug-resistant enteroaggregative Escherichia coli with persistent diarrhea in Kenyan children, stool specimens were obtained from 862 outpatients under 5 years of age from July 1991 to June 1993. E. coli O44 was identified as the sole bacterial pathogen in four patients experiencing at least 14 days of fever, vomiting, and diarrhea. Disk diffusion testing showed...
متن کاملThe microbiology of bacterial peritonitis due to appendicitis in children
AIM The aim of this study was to investigate the microbiology of secondary bacterial peritonitis due to appendicitis and the appropriateness of current antimicrobial practice in one institution. METHODS A 14-year retrospective single-centre study of 69 consecutive paediatric patients (age 1-14 years) with appendicitis-related peritonitis and positive peritoneal specimen cultures was conducted...
متن کاملSusceptibility testing of Escherichia coli isolates from urines: are we at risk of reporting false antibiotic resistance to co-amoxiclav?
Sir, The BSAC recently published a change to the recommended inhibition zone diameter breakpoint for testing susceptibility of Enterobacteriaceae to amoxicillin/clavulanate (co-amoxiclav), whereby the maximum zone diameter for inferring resistance was increased from 14 to 20 mm. There was no change to the MIC breakpoint, which remains at 8 mg/L. This change resulted in a significant increase in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of clinical microbiology
دوره 51 7 شماره
صفحات -
تاریخ انتشار 2013